The American Cancer Society is marking the 36th Great American Smokeout on November 17th by encouraging smokers to use the date to make a plan to quit, or to plan in advance and quit smoking for at least that day. Tobacco use remains the single largest preventable cause of disease and premature death in the United States, yet 46 MILLION Americans still smoke. Quitting is hard. Make no mistake about that. But help is available and can increase your chances of succeeding.